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Despite the obvious biologic plausibility, the lack of consistent epidemiological evidence might be due to methodological issues including lack of cohort follow-up time into older adulthood (when lung cancer usually becomes clinically manifest), small sample sizes, selection and recall biases, and lack of adjustment for tobacco use in the statistical modeling

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Pictures on cigarette packs, warning of smoking dangers, increased quit attempts among smokers June 6, 2016 Affixing pictures on cigarette packs to illustrate the dangers of smoking increased attempts by smokers to quit, according to the findings of a University of North Carolina study published online June 6 by JAMA Internal Medicine